Abstract

Purpose

This meta-analysis was conducted to determine the prevalence and risk factors of fatigue in type 1 and type 2 diabetes mellitus (DM).

Methods

Observational studies reporting the prevalence and risk factors of fatigue in type 1 or 2 DM were systematically searched for in PubMed, Embase, CINAHL Plus, Cochrane Trial, and ProQuest Dissertation and Theses databases. Data were extracted by two independent reviewers. A random-effect model was used for data analysis.

Findings

We included 19 studies involving 7131 patients with type 1 DM and 32 studies involving 34,994 patients with type 2 DM in the study. The pooled prevalence of fatigue in type 1 and type 2 DM was 44% and 50%, respectively. The Asia–Pacific region (e.g., Japan and Australia), South America, and Africa lacked reports regarding fatigue prevalence in type 1 DM, and North Asia and Southeast Asia lacked reports of fatigue prevalence in type 2 DM. Depression and physical activity were the only two variables significantly correlated with fatigue in both type 1 and type 2 DM (all p < 0.05).

Conclusions

Approximately half of the patients with type 1 or type 2 DM experienced fatigue, with the prevalence of 44% and 50%, respectively. Our findings regarding its risk factors can provide an evidence-based approach for managing fatigue in DM patients.

Clinical relevance

This meta-analysis emphasizes the importance of fatigue management in patients with type 1 and type 2 DM. Most significantly, our results on risk factors related to fatigue in diabetes can contribute to the development of evidence-based strategies for managing fatigue in individuals with DM.

摘要翻譯（僅供參考）

目的

該薈萃分析旨在確定 1 型和 2 型糖尿病 (DM) 中疲勞的患病率和危險(xiǎn)因素。

方法

在 PubMed、Embase、CINAHL Plus、Cochrane 試驗(yàn)和 ProQuest 論文和論文數(shù)據(jù)庫中系統(tǒng)地搜索了報(bào)告 1 型或 2 型 DM 疲勞患病率和危險(xiǎn)因素的觀察性研究。數(shù)據(jù)由兩名獨(dú)立審查員提取。隨機(jī)效應(yīng)模型用于數(shù)據(jù)分析。

發(fā)現(xiàn)

我們納入了 19 項(xiàng)研究，涉及 7131 名 1 型 DM 患者，32 項(xiàng)研究涉及 34,994 名 2 型 DM 患者。1 型和 2 型 DM 的疲勞總患病率分別為 44% 和 50%。亞太地區(qū)（如日本和澳大利亞）、南美和非洲缺乏 1 型糖尿病疲勞患病率的報(bào)告，北亞和東南亞缺乏 2 型糖尿病疲勞患病率的報(bào)告。抑郁和體力活動(dòng)是唯一與 1 型和 2 型糖尿病患者的疲勞顯著相關(guān)的兩個(gè)變量（所有p  < 0.05）。

結(jié)論

大約一半的 1 型或 2 型 DM 患者出現(xiàn)疲勞，患病率分別為 44% 和 50%。我們關(guān)于其風(fēng)險(xiǎn)因素的發(fā)現(xiàn)可以為管理 DM 患者的疲勞提供一種循證方法。

臨床相關(guān)性

該薈萃分析強(qiáng)調(diào)了疲勞管理對 1 型和 2 型 DM 患者的重要性。最重要的是，我們關(guān)于糖尿病疲勞相關(guān)風(fēng)險(xiǎn)因素的結(jié)果有助于制定循證策略來管理糖尿病患者的疲勞。

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關(guān)鍵詞:

患病率,糖尿病,分析,疲勞,評(píng)價(jià),DM,數(shù)據(jù),管理

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