孕期增重過度對(duì)子代健康影響的研究進(jìn)展
2.內(nèi)蒙古自治區(qū)婦幼保健院,內(nèi)蒙古 呼和浩特 010020Effects of excessive weight gain during pregnancy on offspring health: a reviewJI Wenhui1,2, CHANG Jinke1, LI Tao11. Graduate School of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010107, China;
2. Maternal and Child Health Hospital of Inner Mongolia Autonomous Region, Hohhot, Inner Mongolia 010020, China 摘要參考文獻(xiàn) 相關(guān)文章Metrics 摘要 孕期增重過度已經(jīng)成為嚴(yán)重影響產(chǎn)婦健康的全球性臨床及公共衛(wèi)生問題。孕期增重過度不僅會(huì)增加剖宮產(chǎn)率,引起不良妊娠結(jié)局,還可影響子代發(fā)育和健康。本文對(duì)孕期增重過度對(duì)子代健康的影響及機(jī)制進(jìn)行綜述,發(fā)現(xiàn)孕期增重過度增加子代罹患肥胖、心血管疾病、呼吸道感染疾病、糖尿病、多囊卵巢綜合征和心理疾病的風(fēng)險(xiǎn);病理生理學(xué)機(jī)制包括炎癥反應(yīng)、腸道菌群失調(diào)和表觀遺傳學(xué)等,但尚需更多的研究證實(shí)。今后研究需進(jìn)一步探討孕期不同階段增重過度對(duì)子代健康的影響,為合理控制孕期增重和促進(jìn)子代健康提供依據(jù)。服務(wù)把本文推薦給朋友加入引用管理器 E-mail AlertRSS作者相關(guān)文章冀文慧 常進(jìn)科 李弢關(guān)鍵詞 :孕期增重過度, 宮內(nèi)環(huán)境不良, 子代健康 Abstract:Excessive gestational weight gain has already become a global clinical and public health problem that seriously affects maternal health. Excessive gestational weight gain not only increases the cesarean section rate and induces adverse pregnant outcomes, but also affects offspring development and health. This article reviews the effects of excessive weight gain during pregnancy on offspring health and its underlying mechanisms. Excessive gestational weight gain may increase the risk of obesity, cardiovascular diseases, infectious diseases of the respiratory tract, diabetes, polycystic ovary syndrome, mental or psychological illness among offspring, and the pathophysiological mechanisms include inflammatory response, intestinal flora dysbiosis and epigenetics theory. However, further studies are required to validate these hypotheses and to evaluate the effect of excessive weight gain at different gestational stages on offspring health, so as to provide insights into reasonable management of weight gain during pregnancy and improvements of offspring health.Key words:excessive gestational weight gain poor intrauterine environment offspring health收稿日期: 2023-05-10 修回日期: 2023-07-16 出版日期: 2023-09-10基金資助:內(nèi)蒙古自治區(qū)衛(wèi)生健康科技計(jì)劃項(xiàng)目(202202093)通信作者:李弢,E-mail:1587966757@qq.com 作者簡(jiǎn)介: 冀文慧,碩士研究生在讀
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Abstract
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Shared Discussed相關(guān)知識(shí)
孕前肥胖、孕期增重過度與子代健康
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