WEI Fang-mei, CHEN Chun, LI Chao, FU Xiong. Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds[J]. Science and Technology of Food Industry, 2018, 39(21): 299-305. DOI: 10.13386/j.issn1002-0306.2018.21.053

Citation: WEI Fang-mei, CHEN Chun, LI Chao, FU Xiong. Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds[J]. Science and Technology of Food Industry, 2018, 39(21): 299-305. DOI: 10.13386/j.issn1002-0306.2018.21.053

桑葉提取物、茶多酚及其復(fù)配物的抗氧化和降血糖活性

華南理工大學(xué)食品科學(xué)與工程學(xué)院, 廣東廣州 510640

詳細(xì)信息

作者簡(jiǎn)介:

韋芳媚(1991-),女,碩士研究生,研究方向:功能碳水化合物,E-mail:18819455753@163.com。

通訊作者:

扶雄(1971-),男,博士,教授,研究方向:功能碳水化合物,E-mail:lfxfu@scut.edu.cn。

中圖分類號(hào): TS201.4

計(jì)量 文章訪問數(shù):  0393 HTML全文瀏覽量:  059 PDF下載量:  016 出版歷程 收稿日期:  2018-01-23 網(wǎng)絡(luò)出版日期:  2020-11-24 刊出日期:  2018-10-31

Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds

School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China

摘要

摘要: 為探討桑葉提取物(MLE)、茶多酚(TP)及其復(fù)配物的抗氧化和降血糖活性,本文考察了MLE、TP及其復(fù)配物對(duì)DPPH和ABTS+自由基的清除能力和糖尿病關(guān)鍵酶(豬胰腺α-淀粉酶、鼠小腸蔗糖酶和麥芽糖酶)的活性抑制能力。結(jié)果表明,TP、MLE-TP復(fù)配物以及MLE的抗氧化能力依次減弱,其中MLE-TP復(fù)配物的抗氧化能力表現(xiàn)為拮抗作用。MLE-TP復(fù)配物對(duì)糖尿病關(guān)鍵酶的抑制作用均優(yōu)于單獨(dú)MLE和TP。復(fù)配物MLE:TP=2:1(w/w)對(duì)α-淀粉酶的聯(lián)合指數(shù)CI為0.531,復(fù)配物MLE:TP=1:1(w/w)對(duì)蔗糖酶和麥芽糖酶的CI分別為0.429和0.452。MLE-TP復(fù)配物可以提高糖尿病關(guān)鍵酶的抑制效果,起到協(xié)同降血糖的作用。MLE和TP的協(xié)同降糖功效,為開發(fā)安全和高效的天然降血糖功能食品和相關(guān)藥物提供理論依據(jù)。

Abstract: To investigate the antioxidant and hypoglycemic activities of mulberry leaf extract(MLE),tea polyphenols(TP)and their compounds,the DPPH and ABTS+ free radicals scavenging activities and inhibitory effects on key enzymes linked to diabetes(porcine pancreatic α-amylase,rat intestinal sucrase and maltase)were applied. The results showed that the antioxidant capacity of TP was the strongest,followed by MLE-TP compounds and MLE. And the MLE-TP compounds showed antagonistic effect in terms of the antioxidant activity. The MLE-TP compounds showed stronger inhibitory effects on the key enzymes of diabetes than MLE and TP. The Combination Index(CI)of MLE-TP compound with the mass ratio of 2:1 to α-amylase was 0.531,and the CI values of MLE-TP compound with the mass ratio of 1:1 to sucrose and maltase were 0.429 and 0.452,respectively. The MLE-TP compounds could enhance the inhibitory effects on the key enzymes linked to diabetes indicating synergistic hypoglycemic effects,which provided a theoretical basis for developing safe and effective natural functional products and related drugs for alleviating the diabetes.

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計(jì)量 文章訪問數(shù):  HTML全文瀏覽量:  PDF下載量:  出版歷程 收稿日期:  2018-01-23 網(wǎng)絡(luò)出版日期:  2020-11-24 刊出日期:  2018-10-31

目錄

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