Wang Zhenjie;Wei Fan;Li Dongjing;Department of Health Management and Medical Care, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academe of Medical Science;  

Objective To investigate the changes of mild abnormalities of blood uric acid and blood lipid levels in health check-up people after non-drug intervention such as implement of health education, management of diet and exercise. Methods The health check- up people were choosed in PUMC hospital from January to June in 2014, who were more than 40 years old, who had mild abnormalities of blood uric acid and blood lipid levels, and preferred to non-drug intervention. A second check-up was arranged after 6 months. The incidences of hyperuricemia, hyperlipidemias, fatty liver,the blood levels of uric acid and TG, LDL-C, HDL-C were compared. Results A total of 124 people were involved, 104 male and 20 female, average age was(59.23±5.48) years old, average period of intervention was(201.1±13.3) d. In the second time of health check-up, the incidence of hyperuricemia was lower in male than that of 6 months before [29.8%(31/104) vs. 42.3%(44/104), P < 0.05]; while the incidence of hyperuricemia in female, high TG, high TC, high LDL-C, low HDL-C, fatty liver were not changed(P all >0.05). The levels of blood TG [(1.33±0.74)mmol/L vs.(1.53±0.80)mmol/L]and blood uric acid [(382.92±64.09)μmol/L vs.(404.19±71.40)μmol/L] were both lower(P <0.05), while the levels of TC, LDL- C, HDL- C had no significant changes(P > 0.05). Conclusion Non- drug management, such as health education, health consciousness promotion and scientific diet, can improve mild abnormalities of TG, and uric acid levels in male. But only food-control is not easy to decrease the levels of LDL-C. Maybe it needs a long period of non-drug management. Or statin according to guideline is useful.

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