首頁資訊 Preparation and functionality of lipase

Preparation and functionality of lipase

來源：泰然健康網(wǎng) 時間：2025年08月04日 05:03

Background

Structured phospholipids are phospholipids with its fatty acid composition modified for the enhancement of physicochemical and nutritional properties. Phospholipids exert stronger biological effects due to its superior bioavailability compared to other lipid forms such as triacylglycerols. Hence, by incorporating functional fatty acids into phospholipid, structured phospholipid could be used as an efficient carrier to increase the absorption of the fatty acid in the body.

Scope and approach

This review focuses on the preparation method of structured phospholipid and the effects of certain parameters on the transesterification efficiency. Information on researches conducted on structured phospholipids over the last 20 years have been compiled to provide information on the materials and parameters used. The analysis methods for the fatty acid and phospholipid profile are required to ascertain the efficiency of the transesterification reaction. Furthermore, it is important to understand the functional benefits of structured phospholipid and the methods used in literature to analyse the metabolism of structured phospholipid in in vitro or in vivo models.

Key findings and conclusion

Structured phospholipid modified to contain functional fatty acids have the potential to be employed as novel treatments for metabolic diseases and other medical applications to improve body function and reduce risk of certain diseases. Lipidomics advancement could help to evaluate the treatment of metabolic diseases and access the health benefits provided by structured phospholipid using in vitro and in vivo models to access specific metabolic pathways.

中文翻譯：

脂肪酶催化的結(jié)構(gòu)化磷脂的制備和功能研究

背景

結(jié)構(gòu)化磷脂是其脂肪酸組成經(jīng)過修飾以增強理化和營養(yǎng)特性的磷脂。與其他脂質(zhì)形式（如三?；视停┫啾?，磷脂具有更強的生物利用度，因此具有更強的生物學(xué)作用。因此，通過將功能性脂肪酸摻入磷脂中，結(jié)構(gòu)化的磷脂可以用作增加體內(nèi)脂肪酸吸收的有效載體。

范圍和方法

本文綜述了結(jié)構(gòu)化磷脂的制備方法以及某些參數(shù)對酯交換效率的影響。過去20年中有關(guān)結(jié)構(gòu)化磷脂的研究信息已經(jīng)匯總，以提供有關(guān)所用材料和參數(shù)的信息。需要脂肪酸和磷脂譜的分析方法來確定酯交換反應(yīng)的效率。此外，重要的是要了解結(jié)構(gòu)化磷脂的功能益處以及文獻中用于在體外或體內(nèi)模型中分析結(jié)構(gòu)化磷脂代謝的方法。

主要發(fā)現(xiàn)和結(jié)論

經(jīng)修飾以包含功能性脂肪酸的結(jié)構(gòu)化磷脂有可能被用作代謝性疾病和其他醫(yī)學(xué)應(yīng)用的新療法，以改善機體功能并降低某些疾病的風(fēng)險。脂質(zhì)組學(xué)的發(fā)展可以幫助評估代謝性疾病的治療方法，并利用體外和體內(nèi)模型來訪問特定的代謝途徑，從而獲得結(jié)構(gòu)化磷脂所提供的健康益處。