Compass Psychological Support Model for COMP360 Psilocybin Treatment of Serious Mental Health Conditions.
American Journal of Psychiatry ( IF 15.1 ) Pub Date : 2025-01-01 , DOI: 10.1176/appi.ajp.20230884
Namik Kirli? 1 , Molly Lennard-Jones 1 , Merve Atli 1 , Ekaterina Malievskaia 1 , Nadav L Modlin 1 , Stephanie Knatz Peck 1 , Alice Gaillard 1 , Guy M Goodwin 1 , Don Koelpin 1

The psychedelic experience can be challenging. There is a need for a structured framework for providing psychological support to individuals with mental health conditions receiving investigational psilocybin treatment. The primary benefit of such a framework is to support a safe and meaningful psilocybin experience. It also enables future research on the facets of psychological support and/or psychotherapy that most optimally complement psilocybin treatment. The authors describe the Compass Psychological Support Model (CPSM), currently used to support participants with treatment-resistant depression in Compass-sponsored clinical trials of investigational COMP360 psilocybin treatment. The authors also outline the therapist training, mentoring, and fidelity assessment programs they have developed to ensure the quality and consistency of the CPSM delivery.

中文翻譯：

COMP360裸蓋菇素治療嚴(yán)重心理健康狀況的指南針心理支持模型。

迷幻體驗(yàn)可能具有挑戰(zhàn)性。需要一個(gè)結(jié)構(gòu)化的框架，為接受研究性裸蓋菇素治療的心理健康問題個(gè)體提供心理支持。這種框架的主要好處是支持安全且有意義的裸蓋菇素體驗(yàn)。它還使未來對(duì)心理支持和/或心理治療方面的研究成為可能，這些方面最有效地補(bǔ)充了裸蓋菇素治療。作者描述了 Compass 心理支持模型 （CPSM），該模型目前用于在 Compass 贊助的研究性COMP360裸蓋菇素治療臨床試驗(yàn)中支持難治性抑郁癥參與者。作者還概述了他們?yōu)榇_保 CPSM 交付的質(zhì)量和一致性而制定的治療師培訓(xùn)、指導(dǎo)和保真度評(píng)估計(jì)劃。

更新日期：2025-01-01

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