摘要: 應(yīng)激是生物體對外源或內(nèi)源刺激的一種非特異的適應(yīng)性反應(yīng)，有助于維持機(jī)體的內(nèi)環(huán)境穩(wěn)態(tài)和正常的生理活動。當(dāng)應(yīng)激反應(yīng)的程度超過了機(jī)體的適應(yīng)能力時，會誘發(fā)多種生理或心理疾病。應(yīng)激醫(yī)學(xué)以應(yīng)激反應(yīng)誘發(fā)的各種疾病為研究對象，闡釋應(yīng)激狀態(tài)下的生理、病理過程及應(yīng)激損傷機(jī)制，并探索應(yīng)激相關(guān)疾病的預(yù)防和治療手段。本文將從應(yīng)激反應(yīng)的概念入手，總結(jié)近年來關(guān)于應(yīng)激反應(yīng)在多種生理或病理狀態(tài)下的調(diào)控機(jī)制和生物學(xué)功能的研究結(jié)果，探討應(yīng)激醫(yī)學(xué)最新研究進(jìn)展。

Abstract: Stress is an nonspecific adaptive response to endogenous or exogenous stimuli, which is commonly applied by organisms to maintain their internal homeostasis and normal physiological functions. When the extent of stress response surpasses the threshold that the organism can adjust to, a variety of physiological or psychological diseases can be induced by stress response. Stress medicine focuses on investigating the mechanisms underlying the development and progression of the diseases induced by stress response, aiming to find ways to prevent and treat stress-related diseases. Here, we will start with an introduction of stress response, then review the recent advances of stress medicine by discussing the latest research advances in the regulatory mechanisms and biological functions of stress response under various physiological or pathological conditions.

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